One study conducted on non-obese, non-diabetic NASH individuals showed a direct association between saturated fat intake, derived indices of insulin resistance, and the postprandial rise of triglycerides, suggesting a shared pathological ground between nutrition, fats, and insulin activity, in the absence of overt metabolic-related morbidities [38]. The gene discussed is INS; the disease is metabolic dysfunction-associated steatohepatitis.