GEPIA2 database (http://gepia2.cancer-pku.cn/#index, accessed on 20 April 2021) analyses showed that expression of CGNL1 was significantly downregulated in cervical squamous cell carcinoma, esophageal carcinoma, and lung squamous cell carcinoma, suggesting that CGNL1 is downregulated in human squamous cell carcinoma. This evidence concerns the gene CGNL1 and carcinoma of esophagus.