VPS13B and Choreoacanthocytosis: Humans express four different VPS13 paralogs, designated A through D. Mutations in VPS13A, VPS13B, VPS13C and VPS13D are associated with the neurodegenerative disorder Chorea-Acanthocytosis (ChAc), Cohen Syndrome, Parkinson’s Disease, and a form of cerebellar ataxia, respectively [2,3,4,5,6,7].