The former encodes the homonymous transmembrane protein, which along with related astroactin-1 (ASTN1) (1q25.2) has a key role in glial-directed neuronal migration during the embryonal formation of the neocortex [89] while the latter is engaged in functional control of dysbindin—a protein intimately involved in the genetics of schizophrenia [90] and influencing glutamate and dopamine signalization [91]. The gene discussed is ASTN1; the disease is schizophrenia.