Similarly, in the BPD-alcohol abuse phenotype Mosheva et al. (2019) [87] have recently reported a SNP (rs1034936) within the CACNA1C gene which codes the α1-subunit of the L-type voltage-gated calcium channel and has been implicated in various mental disorders (including MDD and BPD) but also in alcohol effects on CNS. This evidence concerns the gene CACNA1C and major depressive disorder.