In this regard, cardiac hypertrophy due to catecholamines is elicited by the activation of both β-adrenoceptor–Gs protein–adenylyl cyclase and α-adrenoceptor–Gq protein–phospholipase C pathways whereas that induced by angiotensin II involves Ang II receptor–Gq protein–phospholipase C system. Here, AGT is linked to cardiac hypertrophy.