Specifically, PAX3-FOXO1 not only plays chromatin-level roles establishing a myoblastic super enhancer landscape, but also drives the transcription of both the glucose transporter 4 (GLUT4) gene (augmenting glucose uptake by cancer cells) and carnitine palmitoyltransferase (CPT1A) (external mitochondrial enzyme responsible for acyl carnitines production) gene (facilitating lipid degradation and subsequently providing cancer cells the energy necessary to migrate and metastasize) [32]. The gene discussed is FOXO1; the disease is cancer.