CIAPIN1 and cholangiocarcinoma: The results showed that the overall survival of CCA patients with high serum CIAPIN1 level was significantly shorter than that of the patients with the low serum CIAPIN1 level, with the median estimations of survival time of 441 ± 49 days (95% CI: 344–538) and 898 ± 289 days (95% CI: 332–1464), respectively; p = 0.001 (Figure 5a).