In neovascular AMD, a post-hoc analysis of the MARINA (Minimally Classic/Occult Trial of the anti-VEGF Antibody Ranibizumab in the Treatment of Neovascular AMD) and ANCHOR (Anti-VEGF Antibody for the Treatment of Predominantly Classic Choroidal Neovascularization in AMD) clinical trials demonstrated that cataract surgery was beneficial for eyes with an average improvement of >10 logMAR letters [5]. This evidence concerns the gene VEGFA and age-related macular degeneration.