BRAF and malignant colon neoplasm: Bioinformatics analysis of proteins specifically up-regulated in BRAF-mutated cells revealed several cellular events that could be potentially associated with the BRAFV600E mutation in colon cancer cells including cytoskeleton remodeling, cell–cell adhesion, transcriptional and epigenetic dysregulations, increased ribosome biogenesis and protein synthesis, positive regulation of the cell cycle, centrosome cycle and mitosis, mitochondrial biogenesis and metabolic alterations linked with increased activity of the enzymes regulating methionine and serine biosynthesis.