MGMT and central nervous system cancer: Furthermore, we have added the subgroup analysis of patients with MGMT positive gliomas and found similar results: FLAIR/T2 volume showed a significant difference between iMRI and early MRI (FLAIR p = 0.009 and T2 p = 0.015), between ultra-early and early MRI (FLAIR p = 0.013 and T2 p = 0.005) and between early and late MRI (FLAIR p = 0.007 and T2 p = 0.011).