OLR1 and atherosclerosis: Two experiments support the oxidative LDL modification hypothesis: firstly, it was demonstrated that oxidized-LDL (ox-LDL) causes damage to cultured endothelial cells [25,26]; secondly, ox-LDL was recognized by different scavenger receptors (Lectin-like oxidized LDL receptor-1 (LOX-1) including scavenger receptors that bind LDL (CD36), scavenger receptors for phosphatidylserine and oxidized LDL in human atherosclerotic lesions (SR-PSOX), and the multifunctional receptor in atherosclerosis (SR-A macrophage receptors)), which mediates the influx of lipids into macrophages.