EGFR and lung adenocarcinoma: Aberrant expression of HER1 caused lung adenocarcinoma development in doxycycline-inducible hEGFRL858R (CCSP-rtTA;Tet-O7-hEGFRL858R), hEGFRDEL (CCSP-rtTA;Tet-O7-hEGFRDEL), and hEGFRVIII (CCSP-rtTA;TetO7-hEGFRVIII) mice [100].