KRAS and neoplasm: Additionally, in the MeIQx-, urethane- and X-ray-treated models, G/C→C/G (AH), A/T→T/A (Ad), and A/T→T/A (Ad) transversions in Kras, respectively, were detected in a neoplasm, while EGFR mutations with amino acid substitution were detected in X-ray-induced tumors (4/12; 33%) [46].