Myositis-specific autoantibodies include anti-ARS, anti-MDA5, anti-signal recognition particle (SRP), anti-Mi-2, anti-transcriptional intermediary factor (TIF)-1γ, anti-nuclear matrix protein (NXP)-2, anti-3-hydroxy-3-methylglutaryl-coenzyne A reductase (HMGCR), and anti-small ubiquitin-like modifier 1 activation enzyme (SAE) [6]. The gene discussed is IFIH1; the disease is myositis disease.