We correlated the impact of FENDRR on enhancing NF-κB, intratumoral T cells, and pro-inflammatory cytokine expressions (Interleukin 1 β (IL1β), Tumor necrosis factor α (TNFα), Interferon γ (IFNγ), and transcription factor 1 (TCF1)) in immunogenic murine C26 colon and poorly immunogenic B16 melanoma tumors [17]. The gene discussed is TNF; the disease is melanoma.