To provide additional validation for our subtype classifier, we predicted the subtype of 14 of the matched samples taken at AML relapse where the diagnostic sample was MLL/KMT2A-rearranged, t(8;21)/RUNX1-RUNX1T1, NK or inv(16)/CBFB-MYH11. This evidence concerns the gene MYH11 and acute myeloid leukemia.