were observed in both study groups, with mean WBC (p < 0.0001), ALT (p < 0.0001), AST (p < 0.0001), ALP (p = 0.012), LDH (p < 0.0001), PT (p < 0.0001), procalcitonin (p < 0.0001), CRP (p < 0.0001), and HCV viral load (p < 0.0001) being significantly higher and platelet count significantly lower (p < 0.0001) in COVID-19 patients with active HCV infection. This evidence concerns the gene CRP and COVID-19.