GPT and COVID-19: A multivariate analysis (Table 3) was conducted to assess the risk factors for liver impairment and all-cause mortality in COVID-19 patients with chronic hepatitis C. Age over 60 years (OR = 2.51, 95%CI 1.43–3.02), male gender (OR = 2.36, 95%CI 1.41–3.15), ALT (OR = 3.17, 95%CI 1.61–3.98), procalcitonin (OR = 2.88, 95%CI 1.45–2.95) levels, and HCV viral load were all independent risk factors for liver impairment.