Contrary to that, we identified distinct gene alterations such as ATM and POLE present in MTUT with comparable frequencies in both ±3%, i.e., bladder (ATM: 13.8, POLE: 6.6) and endometrial cancers (ATM: 13.7, POLE: 12.7), while genes such as PIC3CA or TP53 showed only parallels with one of the two entities. Here, TP53 is linked to endometrial cancer.