Comparing the data with our previous characterization of genetic alterations of intestinal type adenocarcinomas of the bladder, it parallels with clear cell adenocarcinomas, since genes such as ARID1A (intestinal type: 30.6%), CTNNB1 (intestinal type: 11.1%), and MSH6 (intestinal type: 8.3%) showed similar mutational frequencies between both carcinomas [22]. Here, MSH6 is linked to bladder adenocarcinoma.