ZSWIM2 and necrotizing enterocolitis: MEX have been demonstrated to protect IECs from oxidative stress [77,231] and hypoxia [47,72,232,233], stimulate ISC activity [77], improve the proliferation and migration of IECs [72,148,162], improve intestinal barrier function and mucin production [85,92,234], reduce intestinal inflammation [84,92,162,163,235] and lower the incidence and severity of experimental NEC [84,85,92,148,163,235].