By comparing AUCs between CRC vs. non-CRC, it could be seen that MALAT1, PVT1 and E-cadherin with AUC = 0.907, 0.848 and 0.864, respectively, represented diagnostic performance superior to miRNA-101 and miRNA-186 with AUC = 0.686 and 0.702, respectively, in CRC diagnosis (Table 5). The gene discussed is MALAT1; the disease is colorectal carcinoma.