Furthermore, serum MALAT1 and PVT1 discriminated AP from healthy controls with an AUC = 0.965, 95% CI = 0.7639 to 0.9974, p < 0.0001, with sensitivity of 76%, specificity of 95% at a cutoff > 10.9-fold and an AUC = 0.935, 95% CI = 0 0.6581 to 0.8795, p < 0.0001, with sensitivity of 60%, specificity of 94% at a cutoff > 73.9-fold, respectively (Figure 4A–F). The gene discussed is PVT1; the disease is alkaline phosphatase measurement.