We found that miRNA-101 with E-cadherin decreased significantly in the CRC group more than AP and healthy control, which was matched with preceding research which reported that MALAT1 induces EMT through different mechanisms, e.g., the Wnt/β-catenin [35], Ezh2-Notch1 [39] and TGF-β signaling pathways [40]. This evidence concerns the gene NOTCH1 and colorectal carcinoma.