Moreover, it showed a positive correlation with miRNA-101 and miRNA-186 and an inverse correlation with MALAT1 and PVT1; these correlations may prove that a decrease in E-cadherin expression in the primary tumor is correlated with the ability of the tumor to spread, implying PVT1/miRNA-186 and MALAT1/ miRNA-101 in this context. The gene discussed is PVT1; the disease is neoplasm.