NEDD4L and interstitial lung disease specific to childhood: These data further substantiate an important role of Nedd4-2 in normal lung development and lung health, and have established a mouse model of chILD that may serve as a useful tool for studies of the complex in vivo pathogenesis, the identification of biomarkers and therapeutic targets, as well as preclinical evaluations of novel therapeutic strategies that are urgently needed to improve the clinical outcome of patients with chILD [13].