Several reports indicated that targeting pro-apoptotic and anti-apoptotic signaling pathways in cancers along with multiple key enzymes required for cancer survival and spread, such as TrxR, GSHR, inositol-3-phosphate synthase, phosphatidylinositol-3-kinase (PI3K)/protein kinase B (Akt) and a Ras/extracellular kinase regulated by signaling (ERK), represent a unique approach that disrupts the evolutionary dynamics of the cancer ecosystem [14]. Here, AKT1 is linked to cancer.