However, to perform molecular analyses on pancreatic tumor tissues can be challenging, mainly because of the paucity of biological material from traditional fine needle aspirations (FNA) or endoscopic ultrasound (EUS) biopsies in advanced cases [22] and only few data are available about technical aspects related to BRCA1/2 testing on pancreatic formalin-fixed and paraffin-embedded (FFPE) specimens [23]. The gene discussed is BRCA1; the disease is pancreatic neoplasm.