We designed a microarray for HCC diagnosis that includes various TAAs, such as tumor suppressors p53, Ink4a/p16, NPM1/B23, CAPERα/HCC1.4, and oncoproteins, including IMP1, IMP2/p62, IMP3/Koc, CIP2A/p90, RalA, c-Myc, survivin, cyclin B1, 14-3-3ζ, and MDM2. This evidence concerns the gene CDKN2A and hepatocellular carcinoma.