Obesity gene panel analysis of 57 obesity-associated genes revealed a homozygous variant NM_003097.3(SNRPN):c.193C>T, p.(Arg65Trp) in exon 6 of the SNURF-SNRPN gene, changing CGG into TGG (Figure 2). This evidence concerns the gene SNRPN and obesity due to melanocortin 4 receptor deficiency.