MAPT and Alzheimer disease: In the following years, a host of tauopathies were induced in WTs, from 3R and 4R tauopathies AD and PART, through to 4R tauopathies including aging-related tau astrogliopathy (ARTAG), GGT, PSP, CBD, AGD, and familial FTD linked to the P301L MAPT mutation [18,110,120,121,122,123,124,125,126,127].