To investigate the effect of AMI-1 on lung cancer cell viability compared to normal epithelial cells, both lung cancer cells and HBEpC cells were treated with AMI-1, Cis, or a combination of two drugs, and apoptosis was determined at 72 h by annexin V/propidium iodide staining, as shown in Figure 5A–C. The gene discussed is ANXA5; the disease is lung carcinoma.