Interleukin and chemokine receptors IL4R and CXCR2—pivotal molecules in alternative macrophage activation and immunosuppression—show significantly higher expression in the NE-low tumor phenotype compared to NE-high (8.71 ± 2.16 vs. 7.88± 1.84, p = 0.009 and 5.5 ± 1.02 vs. 3.83 ± 2.11, p < 0.001, Figure S6). The gene discussed is CXCR2; the disease is neoplasm.