Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 [62] are all inherent in Th1-biased immune responses, including in the recruitment of tumoricidal immune cells [63], subsequently hallmarking the role of the central pro-inflammatory factors in immune-oasis SCLC according to our data (Figure 7). This evidence concerns the gene CXCL9 and small cell lung carcinoma.