Regarding the field of psychiatric research, reelin levels have been studied in the brains of patients with autism spectrum disorder, bipolar disorder, schizophrenia, Alzheimer’s disease, and major depression, with diverse results since the tissue analyses targeted reelin levels in different regions, such as the hippocampus, frontal cortex, etc. [27]. This evidence concerns the gene RELN and early-onset autosomal dominant Alzheimer disease.