BMI1 and neoplasm: Considering BMI-1’s involvement in cellular proliferation and tumor progression, this gene has been identified, as expected, in a large variety of human tumors, such as: lymphoma [12,13,14], brain [15], prostate [16], oropharynx and nasopharynx [10,17,18], breast [19,20], bladder [11], gastric [21], pancreas [22], esophagus [23], lungs [24,25], head and neck cancers [26], malignant melanoma [27], pleomorphic adenoma [28], and also displaying a prognosis value in mielodysplastic syndromes [29] and in gallbladder cancer [30].