Similar results were confirmed in the dual-luciferase reporter assays of ITGB1 and miR-29c-3p, indicating that ITGB1 was directly regulated by miR-29a-3p, miR-29b-3p and miR-29c-3p in ICC cells (Figure 7B). Here, ITGB1 is linked to intrahepatic cholangiocarcinoma.