EMT in PCa is associated with resistance to chemotherapy, orchestrated mainly by the action of transcription factors such as ZEB1 and ZEB2, as well as by downregulation of “pro-epithelial” miRNAs, such as miR-143, miR-145, miR-29b, miR-34b, and the miR-200 family [235,246]. This evidence concerns the gene ZEB1 and posterior cortical atrophy.