CDKN2A and neoplasm: Similarly, a recent in vitro study evaluated the anti-tumor activity of oncolytic Schwarz strain of measles virus in MPM cell lines and showed that CDKN2A homozygous deletions are frequently associated with the homozygous deletions of type I interferon (IFN-I) genes, which are located in the same 9p21.3 chromosome region, thus rendering these cell lines more sensitive to measles virus infection [135].