This is not surprising, taking into consideration that myosin is the most abundant protein in the myocardium and that myosin has also been identified as a key autoantigenic target also in postinfectious immune-mediated diseases, such as rheumatic heart disease and Chagas cardiomyopathy [23,30,31,32]. This evidence concerns the gene MYH14 and Chagas cardiomyopathy.