Thus, our findings suggest that in lymphocytic, giant-cell and sarcoidotic myocarditis, as well as in arrhythmogenic right ventricular cardiomyopathy and Brugada syndrome, all highly arrhythmogenic diseases, with similar and often overlapping clinical features, autoimmunity to myosin and intercalated disk proteins may be a common immunopathogenic link. Here, MYH14 is linked to myocarditis.