Notably, Syk (Figure 6E), PLZF (Figure 6F) and Helios (Figure 6G) expression, cytokine stimulation (Figure S12A), and ADCC (Figure S12B) were similar in FcεRIγ− adaptive NK cells from patients with chronic HBV infection (non-cirrhotic) and with HBV-associated HCC (Tables S1 and S4). This evidence concerns the gene IKZF2 and hepatocellular carcinoma.