Non-clinical studies in syngeneic mouse tumours (ID8-R) and human xenograft (OVCAR3, SKOV3) ovarian tumour models transplanted intraperitoneally with murine MSCs stably expressing murine IFN-β showed that these cells could preferentially target the tumour sites and induce a significant reduction in tumour size compared to controls [58]. The gene discussed is IFNB1; the disease is neoplasm.