To study the transcriptomic landscape of circadian clock genes in glioma and any coordinated patterns associated with prognosis, we utilized RNA-seq data from (668 grades 2–4) glioma patient samples (428 IDH-mutant, 233 IDH wild-type, and 7 of unconfirmed IDH status) from The Cancer Genome Atlas (TCGA) [40,41]. Here, CLOCK is linked to central nervous system cancer.