IL6 and Miyoshi myopathy: In addition, proteomic analysis of MM BM-MSC-exos showed elevated levels of oncogenic proteins (such as junction plakoglobin (also known as γ catenin)), cytokines/chemokines (such as interleukin (IL)-6 and C-C motif chemokine ligand (CCL2)), and adhesion molecules (including fibronectin), all of which promote the dissemination of MM cells to the distant BM niche in contrast to HD BM-MSC-exos [20] (Figure 2B).