INS and type 2 diabetes mellitus: The NAFLD etiology is multifactorial and yet incompletely understood, but ultimately appears as determined by the combination of environmental factors, such as excessive adiposity or the presence of type 2 diabetes (T2D) as well as the accumulation of intrahepatic lipids, alterations of energy metabolism, insulin resistance and inflammatory processes, where the genetic make-up may emerge [1,4].