RNA-sequencing of peripheral blood mononuclear cells (PBMCs) from infected, vaccinated, and control goats during early stages of infection identified several differentially expressed (DE) genes between the three different groups, of which many were involved in immune response including IL-18BP, IFN-γ, IL-17A, NOS2, LIPG, and IL-22 [142]. Here, IFNG is linked to infection.