SFRP5 and morbid obesity: Therefore, the main objective of this study was to investigate the specific role of SFRP5 in NAFLD: on the one hand, analyzing serum SFRP5 levels in women with normal weight (NW) and morbid obesity (MO) with and without NAFLD; and on the other hand, analyzing the relative mRNA hepatic abundance of SFRP5 in women with MO with different degrees of NAFLD.