On the one hand, we observed significantly higher mRNA relative expression of WNT5A in the liver of NAFLD patients than those with NL histology, as shown in Figure 5A. Moreover, when we analyzed the hepatic relative mRNA abundance of WNT5A according to different degrees of NAFLD, we found that WNT5A hepatic expression was significantly enhanced in patients with SS than those with NL or NASH (Figure 5B). Here, WNT5A is linked to metabolic dysfunction-associated steatohepatitis.