Biochemical analyses indicated that patients with NW had significantly lower weight, BMI, HbA1c, TG, and alanine aminotransferase (ALT) than NL, SS, and NASH groups; also, levels of insulin, GGT, and alkaline phosphatase (ALP) were lower in NW compared to SS; meanwhile, AST and GGT levels of NW subjects were lower compared to NASH patients. This evidence concerns the gene INS and metabolic dysfunction-associated steatohepatitis.