Along with phosphoinositide-3-kinase regulatory subunit 3 (PIK3R3) and poly(ADP-ribose) polymerase-14 (PARP14) (among others), TRIB2 was up-regulated in sessile serrated polyps (SSA/Ps), while expressed at a lower level in both the right colon and hyperplastic polyps (HPs) samples [74]. The gene discussed is TRIB2; the disease is hyperplastic polyp.