Levels of HMGB1 has been linked to the efficacy of treatment in patients with breast cancer with better efficiency than monitoring other cancer biomarkers such as CA 15-3 and CEA [167] Accordingly, Rapoport and Anderson have written an interesting review on the association between ICD and treatment success, where they address not only DAMPs but also other immune cell components that may help in predicting the success of treatments [168]. Here, HMGB1 is linked to breast cancer.