Statistical analysis performed only among HIV+ patients without known coinfections showed IFN-γ level decreased at week 8 [16.28, 7.333–43.34, p = 0.0247], 12 [25.27, 11.79–41.91, p = 0.0271] and 24 [13.46, 6.936–28.5, p = 0.0396] compared to week 0 [87.83, 65.16–158.4] (Figure S1B), suggesting that IFN-γ levels decreased after ART initiation only among patients without coinfections. This evidence concerns the gene IFNG and coinfection.