INS and type 1 diabetes mellitus: In particular, ADSC injection alone per se led to a partial retrieval of penis activity (i.e., ↓ cell apoptosis, restored cavernous endothelium, etc.), but the favourable changes in penile tissue with functional recovery of erection were achieved only after insulin administration, which led to a reduction in AGE products within the penis compartment as observed in rats with T1D [62].