Since we did not show differences in the expression of monocarboxylate transporter 2 (MCT2), which is involved in the transport of lactate to neurons, or MCT4, which is responsible for the transport of lactate to astrocytes, in any of the study groups, the metabolic changes observed in the model of coexisting depression and hypothyroidism were not due to changes in lactate transport. The gene discussed is SLC16A7; the disease is major depressive disorder.