miRNA functions in CRC development are mediated via target genes and key pathways regulating cell proliferation and migration, such as the Wnt/β-catenin, PI3K/Akt/mTOR, TGF-ß (transforming growth factor beta) and EGFR (epidermal growth factor receptor) signalling pathways [216,217]. The gene discussed is AKT1; the disease is colorectal carcinoma.