PTEN and breast cancer: A study on BC showed that suppression of MAGI2 expression by miR-101 (through translational repression instead of mRNA degradation) reduces PTEN activity and AKT activation [119], while in lung adenocarcinoma cells, miR-134, miR-487b, and miR-655 were found to target MAGI2, leading to loss of PTEN stability [55].