In another study on PCa, MAGI2 mRNA gene expression levels were found significantly downregulated in a cohort of clinical PCa samples and cell lines, however, in this case, the downregulation of MAGI2 was not correlated to PTEN mRNA expression, suggesting that different genomic events caused distinct chromosomal aberrations in each gene [122]. This evidence concerns the gene PTEN and posterior cortical atrophy.