Our group also reported that treatment of human MCF-7 breast cancer cells (which harbor wt alleles of p53) with doxorubicin, a well-known inducer of p53, induced the expression of galectin-7 at both the mRNA and protein levels and that this induction was abrogated following knockdown of wt p53 [20]. The gene discussed is LGALS7; the disease is breast cancer.