Intriguingly, the expression of the proinflammatory cytokines, for example, IL‐4, IL‐6, IL‐1β, and TNFα, is often rescued/normalized in previously medication‐naive BD patients following chronic treatment with lithium (Boufidou et al., 2004; Knijff et al., 2007; Rapaport et al., 1999). Here, IL1B is linked to Behcet disease.