The AUC values of AF APRIL, IL-8, MIP-1α, S100 A8/A9, and TIMP-1 for the prediction of SPTD at <34 weeks of gestation after cerclage were 0.752, 0.715, 0.702, 0.857, and 0.792, respectively (Table 5 and Figure 3). The gene discussed is CCL3; the disease is atrial fibrillation.